Which dietary supplement has been shown to enhance muscle protein synthesis (MPS) with resistance training?

Whey protein is widely recognized for its ability to enhance muscle protein synthesis (MPS) in conjunction with resistance training. This is due to its unique amino acid profile, particularly its high concentration of branched-chain amino acids (BCAAs), especially leucine, which plays a key role in initiating the MPS process. Whey protein is rapidly digested and absorbed, leading to a quick spike in amino acid levels in the bloodstream post-workout. This rapid availability of amino acids is crucial for stimulating MPS, aiding in muscle repair and growth following resistance exercises.

Additionally, research has consistently demonstrated that whey protein supplementation can lead to greater increases in muscle mass and strength when combined with resistance training compared to other protein sources. While other options like casein, egg, and soy protein can also contribute to protein intake and MPS, whey has the most substantial evidence supporting its efficacy in promoting muscle growth, particularly post-exercise.