Which factor is most likely to influence longevity?

Calorie restriction is recognized as a significant factor influencing longevity. Research has shown that reducing calorie intake without leading to malnutrition can extend lifespan in various organisms, including yeast, worms, flies, and even mammals. This effect is thought to be related to the reduction of oxidative stress and inflammation, as well as improvements in metabolic health, which are associated with reduced calorie consumption.

Caloric intake affects the body’s hormonal balance and metabolic processes, thereby potentially extending years of healthy living. Incorporating practices that involve calorie restriction, such as intermittent fasting or reducing portion sizes, can lead to health benefits like improved blood pressure, cholesterol levels, and glucose regulation.

While other choices may contribute to overall health or play a role in wellness, calorie restriction has the most direct and well-researched connection to increased longevity. Daily exercise, for instance, is crucial for maintaining functional fitness and metabolic health, but it may not have the same profound impact on lifespan as calorie intake management does.